• Feng, L. Zhang, J. Lee, C. Kim, G., Liu, F., Petersen, A., Lim, E., Anderson, C., Orland, K., Robertson, G., Eckhardt, L., January, C. and Kamp, T.J. (2021). Long QT Syndrome 2 PAS domain variant induces hERG1a/1b subunit imbalance in patient-specific iPSC-cardiomyocytes. Circulation: Arrhythmia and Electrophysiology. doi:10.1161/CIRCEP.120.009343. Epub 2021 Mar 17.                                                                                                                                                                                                   Abstract | Full Text | PDF
  • Ríos-Pérez EB, Liu F, Stevens-Sostre WA, Eichel CA, Silignavong J, Robertson GA. (2021). A stable cell line inducibly expressing hERG1a/1b heteromeric channels. J Pharmacol Toxicol Methods doi: 10.1016/j.vascn.2021.107081.                Abstract | Full Text | PDF
  • Harley, C.A., Bernardo-Seisdedos, G., Stevens-Sostre, W.A., Jones, D.K., Azevedo, M.M., Sampaio, P., Lorga-Gomes, M., Trudeau, M.C., Millet, O., Robertson, G.A., and Morais-Cabral, J.H. (2021). Conformation sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating. Proc Natl Acad Sci 118 (44) e2108796118;                Abstract | Full Text | PDF


  • Eichel C.A., Rios-Pérez E.B., Liu F., Jameson M.B., Jones D.K., Knickelbine J.J., Robertson, G.A. (2019). A microtranslatome coordinately regulates sodium and postassium currents in the human heart. eLife DOI: 10.7554/eLife.52654 [Epub ahead of print.]

    • F1000 Prime Recommended – Vandenberg J: F1000Prime Recommendation of [Eichel CA et al., elife 2019 8]. In F1000Prime, 14 Nov 2019; 10.3410/f.736834995.793567133. Link
  • Robertson, G.A. and Morais-Cabral, J.H. (2019). hERG function in light of structure. Biophys. J. doi: 10.1016/j.bpj.2019.10.010 [Epub ahead of print.]


  • Castro-Rodrigues, A.F., Zhao, Y., Fonseca, F., Gabant, G., Cadene, M., Gail A. Robertson, G.A. and Morais-Cabral, J.H. (2018). The interaction between the Drosophila EAG potassium channel and the protein kinase CaMKII involves an extensive interface at the active site of the kinase. J. Mol. Biol. 430:5029-5049.                                                                                                 Abstract | Full Text | PDF
  • Jones, D.K.*, Johnson, A.A.*, Roti Roti, E.C.*, Liu, F., Uelmen, R., Jones, E.M.C., Ayers, R.A., Baczko, I., Tester, D., Ackerman, M.J., Trudeau,# M.C. and Robertson, G.A.# (2018). TRIOBP-1 regulates hERG channel surface expression and action potential morphology in the mammalian heart. J. Cell Science. 131:doi: 10.1242/jcs.206730. PMCID:PMC5897710. *Equal contributions. #Corresponding authors.                                                                                                                                                  Abstract | Full Text | PDF


  • Zhao, Y., Goldschen-Ohm, M., Morais Cabral, J., Chanda, B. and Robertson, G.A. (2017). The intrinsically-liganded cyclic nucleotide-binding homology domain promotes KCNH channel activation. J. Gen. Physiol.
    Abstract | Full Text | PDF

  • Pointer, K.B., Elcieri, K.W., Clark, P., Robertson, G.A. # and Kuo, J.S. # (2017). Non-torsadogenic human Ether-a-go-go Related Gene (hERG) inhibitors are associated with better survival for high hERG-expressing glioblastoma patients.Clinical Cancer Research. #Corresponding authors.
    Abstract | Full Text | PDF


  • Liu, F., Jones, D.K., de Lange, W. and Robertson, G.A. (2016). Co-translational association of mRNA encoding subunits of heteromeric ion channels. Proc Natl Acad Sci 113(17):4859-64.
    Abstract | Full Text | PDF

  • Harley, C.*, Starek, G.*, Jones, D.K. *, Robertson, G.A.# and Morais-Cabral, J.H. # (2016). Modulation of hERG gating by antibody fragments uncovers an antiarrhythmic therapeutic strategy. Proc Natl Acad Sci 113(35):9916-21. *Equal contributions. #Corresponding authors.
    Abstract | Full Text | PDF

  • Jones, D.K., Liu, F., Dombrowski, N., Joshi, S.A., and Robertson, G.A. (2016). Dominant-negative consequences of a hERG 1b-specific mutation associated with intrauterine fetal death. Prog Biophys Mol Biol 120(1-3):67-76.
    Abstract | Full Text | PDF


  • Morais-Cabral JH, Robertson GA. (2014) The Enigmatic Cytoplasmic Regions of KCNH Channels. J Mol Biol 427(1):67-76.
    Abstract | Full Text | PDF

  • Jones DK, Liu F, Vaidyanathan R, Eckhardt LL, Trudeau MC, Robertson GA. (2014). hERG 1b is critical for human cardiac repolarization. Proc Natl Acad Sci 111(50):18073-7
    Abstract | Full Text | PDF


  • Robertson, G.A. (2013). High-resolution scanning patch clamp: Life on the nanosurface. [Editorial] Circulation Research112:1088-1090.
    Full Text | PDF


  • Abi-Gerges, N., Holkham, H., Jones, E.M.C., Pollard, C.E.Valentin, J.-P. and Robertson, G.A. (2011). hERG subunit composition determines differential drug sensitivity. British J. Pharmacol. 164(2b):419-32.
    Abstract | Full Text | PDF

  • Trudeau, M.C., Leung, L.M., Roti Roti, E. and ROBERTSON, G.A. (2011). ). hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: A possible mechanism for long QT syndrome J. Gen. Physiol. 138:581-592
    Abstract | Full Text | PDF


  • Fergestad, T., Harinath, S., Bostwick, B., Schaffer, A., Ho, L.L., ROBERTSON, G.A. and Ganetzky, B. (2010). Down and out is an essential regulator of ERG channels in Drosophila. Proc. Natl. Acad. Sci. 107(12):5617-21
    Abstract | Full Text | PDF


  • Sale, H., Wang, J., O’Hara, T.J., Tester, D.J., Phartiyal, P., He, J.-Q., Rudy, Y, Ackerman, M.J. and ROBERTSON, G.A. (2008). Physiological properties of heteromeric hERG 1a/1b channels and a hERG 1b-specific mutation associated with Long QT Syndrome. Circulation Res. 103(7):e81-95
    Abstract | Full TextPDF

  • Wynia Smith, S.L., Gillian-Daniel, A.L., Satyshur, K. and ROBERTSON, G.A. (2008). hERG gating microdomains defined by S6 mutagenesis and modeling. J. Gen. Physiol. 132:507-20.
    Abstract | Full TextPDF

  • Phartiyal, P., Jones, E.M.C. and Robertson, G.A. (2008). ER retention and rescue by heteromeric assembly regulate hERG 1a/1b surface channel composition. J. Biol. Chem. 283: 3702 – 3707.
    Abstract | Full Text | PDF


  • Phartiyal, P., Jones, E.M.C. and Robertson, G.A. (2007). Heteromeric assembly of hERG 1a and 1b subunits occurs cotranslationally via amino terminal interactions. J. Biol. Chem. 282: 9874-9882.
    Abstract | Full Text | PDF


  • Jones, E.M.C., Roti Roti, E.C., Wang, J., Delfosse, S.A. and Robertson, G.A. Cardiac IKr channels minimally comprise hERG 1a and 1b subunits (2004). J. Biol. Chem. 279:44690-44694.
    Abstract | Full Text | PDF


  • Wang, J., Myers, C.D. and Robertson, G.A. (2000). Dynamic Control of Deactivation Gating by a Soluble Amino-Terminal Domain in HERG K+ Channels. J. Gen. Physiol. 115: 749-758.
    Abstract | Full Text | PDF


  • Zhou, Z, Gong., Q., Ye, B., Fan, Z., Makielski, J.C., Robertson, G.A. and January, C.T. (1998). Properties of HERG channels stably expressed in HEK 293 cells. Biophysical J. 74:230-241.
    Abstract | Full Text | PDF


  • London, B., Trudeau, M.C., Newton, K.A., Beyer, A.K., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Satler, C.A. and Robertson, G.A. (1997). Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the cardiac current IKr. Circulation Research 81:870-878.
    Abstract | Full Text


  • Trudeau, M. C., J.W. Warmke, B. Ganetzky, and G.A. Robertson. (1995). HERG, a human inward rectifier in the voltage-gated potassium channel family. Science 269: 92-95.
    Abstract | Full Text | PDF